A goal of any pharmaceutical manufacturer is the pursuit of the most efficient equipment available. This equipment can increase output, reduce downtime, cut costs, and increase overall productivity while also adhering to strict cGMP requirements. The acquisition of this type of efficient equipment is the main purpose of the expansion at Piramal Pharma Solutions, Lexington, Kentucky.
According to recent trends in the market, the global contract pharmaceutical manufacturing industry is increasing at an average annual rate of 7.5% and is predicted to reach $79.24 billion in revenue by the year 2019. The market research firm, Visiongain, also expects a strong expansion in revenue for these companies to continue through 2025. Some key drivers in this growth include a growing demand for treatments based on highly potent active pharmaceutical ingredients (API) and regenerative medicines.
Lyophilization is a process in which water is removed from a product after it is frozen and placed under a vacuum allowing the ice to change directly from solid to vapor without passing through a liquid phase. Typically, this dehydration process is used to preserve a perishable material and/or make the material more convenient for transport. The process usually involves three phases consisting of freezing, sublimation, and desorption.
Studies of extractable and leachable components (E&L) within packaging systems and pharmaceutical container closures have become mandatory to meet the safety requirements for marketed medicines over the past two decades. The regulatory guidance for E&L provides only general recommendations to ensure safety. The development and analysis of E&L for inhalation, ophthalmic, and injectable drug products is challenging since studying them depends on the type of formulation and packaging material being used.
Cancer is a widely known disease involving abnormal and uncontrolled cell proliferation resulting in solid tumor development or blood cancer conditions. Therefore, when it comes to fighting cancer, the aim is to kill the cancerous cells and/or inhibit the uncontrolled proliferation.