Piramal Pharma Solutions Press Releases

Press Releases

Coldstream Partners with Local Company for Manufacture of New Equine Device

Posted on Mon, Apr 15, 2013 @ 10:46 AM by Kathy Sue Bennett in parenteral manufacturing, in sterile manufacturing, in aseptic filling

Photo Caption:  Equinext’s President and CEO, Eric Hauck, with Eric Smart, President and CEO of Coldstream Laboratories in Coldstream’s sterile manufacturing facility.

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Coldstream Laboratories to Attend Informex 2013

Posted on Fri, Feb 08, 2013 @ 10:47 AM by Kathy Sue Bennett in lyophilization, in lyophilized products, in parenteral manufacturing, in sterile manufacturing

Representatives from Coldstream Laboratories will be attending Informex 2013 in Anaheim, CA. The event will take place at the Anaheim Convention Center February 19 - 22, 2013.

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Difficult-to-Lyophilize Products: A Brief Look at Lyophilization Development

Posted on Tue, Dec 18, 2012 @ 12:31 PM by Charles Reichel in lyophilization, in lyophilized products, in product development, in lyocycle optimization

In order to effectively develop a lyophilization cycle, it is important to understand the glass transition temperature (through Differential Scanning Calorimetry “DSC”) and collapse temperature (through Freeze-Drying Microscopy “FDM”) of the formulation between the liquid, glassy, and frozen states.  These values will help define the maximum product temperature that the product can achieve during primary drying in order to prevent collapse or melt back of the product due to incomplete sublimation of unbound moisture and/or solvent.  This should happen prior to the ramp to secondary drying with final removal of the bound moisture and/or solvent. 

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Eric Smart Named President and CEO of Coldstream Laboratories, Inc.

Posted on Mon, Oct 29, 2012 @ 09:09 AM by Kathy Sue Bennett in parenteral manufacturing, in eric smart, in sterile manufacturing

LEXINGTON, KY (Marketwire - October 29, 2012) – Eric W. Smart has been named the new President and CEO of Coldstream Laboratories Inc., the largest sterile pharmaceutical manufacturing facility in Kentucky.

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Spotlight on the West Coast

Posted on Thu, Sep 27, 2012 @ 03:02 PM by Kathy Sue Bennett in parenteral manufacturing, in product development

In April of 2012, Coldstream Laboratories expanded its sales presence to the West Coast with the addition of Heidi Kipers as Business Development Manager.  As Coldstream’s West Coast sales representative, Heidi is based in San Diego, CA, and represents the territory west of the Rocky Mountains. 

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Mobile Isolators in Sterile Manufacturing

Posted on Fri, Sep 07, 2012 @ 05:11 PM by Kathy Sue Bennett in parenteral manufacturing, in isolator technology, in sterile manufacturing, in aseptic filling

The sterile manufacturing facility at Coldstream Laboratories employs unique mobile isolator technology to allow flexibility in executing a wide variety of manufacturing processes. Our isolators facilitate handling of difficult-to-manufacture drug products and ensure the safety of our workforce throughout the production process.  Mobile isolators provide an ISO Class 5 environment for aseptic processing and minimize human contact with the products we manufacture.   This technology allows Coldstream to process a variety of potent drug substances such as cytotoxins in an adaptable alternative manufacturing setting when compared to standard clean rooms.

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Benefits and Challenges of Real-Time Release of Water for Injection

Posted on Mon, Aug 13, 2012 @ 09:32 AM by Angela Harrison, Director of Technical Services in release testing, in sterile manufacturing, in water for injection

Pharmaceutical grade water is the most commonly used ingredient in sterile pharmaceutical manufacturing and acceptable water purity is critical to producing quality final drug product.  Water for Injection (WFI) is water that is purified by distillation or a purification process that is equivalent or superior to distillation in the removal of chemicals and microorganisms.  Pharmaceutical manufacturers are moving from laboratory to on-line analysis for real time water release.  Real-time release can greatly improve efficiencies and cost while allowing for increased quality assurance awareness.  Real-time release of pharmaceutical waters increases system understanding, decreases QC testing, reduces batch risk and improves process controls. 

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Coldstream Laboratories Upgrades Sterile Manufacturing Facility

Posted on Tue, Jul 24, 2012 @ 09:42 AM by Kathy Sue Bennett in lyophilization, in lyophilized products, in sterile manufacturing, in product development

(Lexington, KY—(Marketwire—July 24, 2012) - Coldstream Laboratories, Inc., a Lexington, Kentucky, based pharmaceutical and biotechnology development and manufacturing firm announced today the initiation of significant enhancements to its manufacturing facility.  Work began last week on expanding a number of key systems in the sterile drug product manufacturing plant aimed at improving efficiencies and expanding capacity to produce parenteral products.

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A Successful Showing at BIO International Conference 2012

Posted on Tue, Jun 26, 2012 @ 11:22 AM by Kathy Sue Bennett

Coldstream Labs is excited to announce a successful showing at the BIO International Conference 2012 that took place in Boston, MA, June 18-21, 2012. 

Eric Smart, Executive Vice President; Chris Verbicky, Director of Business Development and Marketing; Heidi Kipers, Business Development Manager; and Kathy Sue Bennett, Marketing Manager; represented Coldstream at the four-day event at the Boston Convention Center.

       Photos from the event which featured Kentucky bourbons, hot browns, Derby pies, and pulled pork biscuits.

Highlights of the show included a Kentucky Derby-themed bourbon tasting where potential clients could sample four premium Kentucky bourbons and have a taste of Kentucky hors d’oeuvres while learning about Coldstream’s parenteral manufacturing services.  Approximately 300 people attended the exhibit hall reception, held on Tuesday evening of the exhibition.  It proved to be a fun and unique way to publicize Coldstream.  Coldstream hopes to host similar receptions at future tradeshows and conferences.

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Coldstream Laboratories Announces Manager of Technology Transfer

Posted on Mon, Jan 23, 2012 @ 09:01 AM by Kathy Sue Bennett

Sholto Maclean Named Manager of Technology Transfer at Coldstream Labs.

LEXINGTON, KY--(Marketwire – Jan 23, 2012) - Coldstream Laboratories, Inc., a provider of drug product research and manufacturing services specializing in high potency and cytotoxic parenteral products, has named Sholto Maclean as Manager of Technology Transfer.

In the newly created position, Maclean will work closely with Coldstream’s pharmaceutical development team to scale up processes for sterile liquid and lyophilized drug products for manufacturing in the company’s sterile manufacturing facility.

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